Devlin DeFrancesco then sent his Andretti Autosport car to 277 mph before Joseph Newgarden – a three-time winner at World Wide Technology Raceway – put everyone into perspective with an effort of 179.660 mph on his ninth lap.
Scott McLaughlinwho finished fourth here last year, closed in on his team-mate with a lap of 179.172mph, and at the time they were the only drivers to reach 195mph at the first turn.
Shortly after that Graham Rahal finished second with an effort of 179.713 mph for Rahal Letterman Lanigan.
Pato O’Ward then completed an AMSP 1-2, just 0.0074sec/0.052mph slower than his team-mate.
Alex Palou, Chip Ganassi Racing Honda
Photo: Phillip Abbott / Images of motor sports
Both were pushed down Alex PaluA qualifying simulation, a lap of 180.208mph before McLaughlin joined them at 180mph, followed by Will Power who went fastest at 180.539 with six minutes to go.
This remained the top speed of the session, although it ended with six drivers north of 180 mph and several drivers had their qualifying simulators ruined by traffic.
Chip Ganassi Racing will be happy with two cars in the top five at what has come to be known as the Penske track.
Autosport Andretti disappointing overall, although De Francesco, who tested alongside his fellow rookies last week, did himself a great credit by being fastest of the quartet in 11thousandslightly ahead Colton Herta and Alexander Rossi.
Takuma Sato and Malyukas were ninth and 13ththousand for Dale Coyne Racing, Malukas turned the most laps with 57.
Qualifying begins at 3:15 p.m. local (central) time.